Navigating the Depths of RNA Genomics Data
Bioinformatics
Looking for inspiration on your next custom RNA genomics project? Explore our interactive ENCODE RBP-eCLIP reports for your RBPs of interest; read our bioinformatics eBlogs to understand the latest RNA genomics tools; and learn about Eclipsebio’s Lunar™ Data Analysis Portal to help tackle your analysis
Let’s Learn
Download ENCODE datasets analyzed by Eclipsebio for your RBP of Interest
- Reports contain data for peaks and motifs
- Explore analyzed results from over 150 RBPs
- Discover motifs specific for your RBP of interest
- Compare your own results to ENCODE
Lunar Data Analysis Portal: Our Pipelines at your Fingertips
- All users can explore Eclipsebio demo RBP-eCLIP data deliverables in Lunar
- Directly download results or navigate through the data in Lunar’s integrated genome viewer
Read eBlogs by Expert Bioinformatics Scientists
- Interested in how we analyze our different technologies? Learn about new & internally developed bioinformatics tools for our latest RNA genomics technologies
- Gain insights into the different ways Eclipsebio examines data as well as general topics in the field of bioinformatics
Download ENCODE datasets analyzed by Eclipsebio for your RBP of Interest
- Reports contain data for peaks and motifs
- Explore analyzed results from over 150 RBPs
- Discover motifs specific for your RBP of interest
- Compare your own results to ENCODE
Lunar Data Analysis Portal: Our Pipelines at your Fingertips
- All users can explore Eclipsebio demo RBP-eCLIP data deliverables in Lunar
- Directly download results or navigate through the data in Lunar’s integrated genome viewer
Read eBlogs by Expert Bioinformatics Scientists
- Interested in how we analyze our different technologies? Learn about new & internally developed bioinformatics tools for our latest RNA genomics technologies
- Gain insights into the different ways Eclipsebio examines data as well as general topics in the field of bioinformatics
eBlogs Written by RNA Experts
2023 | eBlogs
Thanksgiving 2023: Thankful for our customers and team | eBlog
As we come towards the end of the year, we at Eclipsebio are taking time this Thanksgiving holiday to reflect on what we are grateful for. As we have asked our fellow team members what they are thankful for, two topics have come up again and again: our customers performing groundbreaking RNA research… [READ MORE]
2023 | eBlogs
Detection of Functional Small Open Reading Frames with Ribosome Profiling | eBlog
Open reading frames (ORFs) are regions of the transcriptome that have an in-frame start and in-frame stop codon. This means that if a ribosome was to start translating at the start codon and translocate every three bases from codon to codon… [READ MORE]
2023 | eBlogs
The Spooky Secrets of Identifying Protein:RNA Interactions | Halloween eBlog
At Eclipsebio, we aren’t afraid of ghosts! Our RBP-eCLIP services can help you obtain meaningful data about your RBP of interest. RBP-eCLIP is a modified version of eCLIP that includes more quality checkpoints throughout the experiment… [BOO! READ NOW]
2023 | eBlogs
How to Use IGV | Bioinformatics eBlog
Interpretation and visualization of RNA next-generation sequencing data can be very challenging, but with genomics viewers such as the Integrative Genomics Viewer (IGV), you can easily visualize and explore your data. In this blog we will walk through how to use the desktop application… [READ MORE]
2023 | eBlogs
RBP-eCLIP Motif Calling | Bioinformatics eBlog
The simplest definition of a motif is a short, patterned sequence of nucleotides that play some role in the biology of a system. In the case of RBPs, this role is to bind selectively to defined regions of a given RBP’s protein structure enabling RBPs to target specific transcripts and specific gene features… [READ MORE]
2023 | eBlogs
RBP-eCLIP Peak Annotation | Bioinformatics eBlog
The goal of RBP-eCLIP is to identify where an RNA-binding protein (RBP) is binding; these regions are often called peaks due to their mountain-like appearance on a genome browser. After peaks have been called, it is important to determine what genes and gene features are associated with those sites…. [READ MORE]
2023 | eBlogs
RBP-eCLIP Peak Calling | Bioinformatics eBlog
The simplest definition of a motif is a short, patterned sequence of nucleotides that play some role in the biology of a system. In the case of RBPs, this role is to bind selectively to defined regions of a given RBP’s protein structure enabling RBPs to target specific transcripts and specific gene features…. [READ MORE]
2023 | eBlogs
Stranded Libraries | Bioinformatics eBlog
Forward, reverse, sense, antisense, first strand, second strand, unstranded. Different methods for sequencing RNA-Seq data can lead to differently stranded libraries all with different names. This can make it challenging to figure out how different kits compare to one another or what parameters to use with different software tools to make sure you are doing an analysis correctly…. [READ MORE]
2023 | eBlogs
eRibo Pro Peak Differential Expression | Bioinformatics eBlog
A DE analysis is a statistical procedure that identifies differentially up or downregulated genes between two or more conditions or samples. It involves comparing the expression levels of each gene in one group of samples (e.g., disease samples) to the expression levels in another (e.g., healthy samples) to identify genes that have changed across conditions…. [READ MORE]