Navigating the Depths of RNA Genomics Data

Bioinformatics

Looking for inspiration on your next custom RNA genomics project? Explore our interactive ENCODE RBP-eCLIP reports for your RBPs of interest; read our bioinformatics eBlogs to understand the latest RNA genomics tools; and learn about Eclipsebio’s Lunar™ Data Analysis Portal to help tackle your analysis

Let’s Learn
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Download ENCODE datasets analyzed by Eclipsebio for your RBP of Interest

  • Reports contain data for peaks and motifs
  • Explore analyzed results from over 150 RBPs
  • Discover motifs specific for your RBP of interest
  • Compare your own results to ENCODE

Lunar Data Analysis Portal: Our Pipelines at your Fingertips

  • All users can explore Eclipsebio demo RBP-eCLIP data deliverables in Lunar
  • Directly download results or navigate through the data in Lunar’s integrated genome viewer

Read eBlogs by Expert Bioinformatics Scientists

  • Interested in how we analyze our different technologies? Learn about new & internally developed bioinformatics tools for our latest RNA genomics technologies
  • Gain insights into the different ways Eclipsebio examines data as well as general topics in the field of bioinformatics

Download ENCODE datasets analyzed by Eclipsebio for your RBP of Interest

  • Reports contain data for peaks and motifs
  • Explore analyzed results from over 150 RBPs
  • Discover motifs specific for your RBP of interest
  • Compare your own results to ENCODE

Lunar Data Analysis Portal: Our Pipelines at your Fingertips

  • All users can explore Eclipsebio demo RBP-eCLIP data deliverables in Lunar
  • Directly download results or navigate through the data in Lunar’s integrated genome viewer

Read eBlogs by Expert Bioinformatics Scientists

  • Interested in how we analyze our different technologies? Learn about new & internally developed bioinformatics tools for our latest RNA genomics technologies
  • Gain insights into the different ways Eclipsebio examines data as well as general topics in the field of bioinformatics
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eBlogs Written by RNA Experts

2024 | eBlogs

Characterization is key: how to evaluate mRNA therapeutic safety and efficacy

Before release into the clinic mRNA therapeutics need comprehensive characterization. In this eBlog we review several key aspects to profile before release…[READ MORE]

2024 | eBlogs

RNA therapeutics: a review of the future of medicine

RNA therapeutics have revolutionized medicine. In this eBlog we discuss the different types of RNA therapeutics that have received FDA approval…[READ MORE]

2024 | eBlogs

Discovering miRNA regulation with miR-eCLIP

miRNAs are key regulators of expression and translation, however identifying where and how they bind can be a challenge. In this eBlog we reveal how miR-eCLIP can be used to directly profile miRNA activity…[READ MORE]

2024 | eBlogs

Successful mRNA therapeutic design: optimizing for stability and translation

mRNA therapeutics have unlocked the potential for rapid responses to infectious disease, personalized treatments for cancer, and protein replacement for different diseases. To ensure efficacy, specific features need to be included in the therapeutic to promote stability, efficient translation, and to… [READ MORE]

2024 | eBlogs

How to find stalled ribosomes

Monitoring translation dynamics at the gene level can be effectively achieved by employing ribosome profiling techniques, such as Eclipsebio’s eRibo Pro technology…[READ MORE]

2023 | eBlogs

2023: A Year-in-Review

2023 has been an exciting year for RNA and Eclipsebio! The RNA genomics space experienced a number of successes—from fascinating publications to the Nobel Prize in Physiology or Medicine, the importance of RNA to biology and health continues to be… [READ MORE]

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2023

RBP-eCLIP Data Sheet

Enhanced crosslinking and immuno-precipitation followed by high-throughput sequencing (eCLIP) was developed to provide a robust and reproducible framework to map RBP binding sites on RNAs transcriptome-wide.

2023

miR-eCLIP Data Sheet

miR-eCLIP enables the identification of direct miRNA-mRNA interactions transcriptome wide utilizing AGO2 immunoprecipitation, RNA-RNA ligation, and high-throughput sequencing (similar to methods such as CLASH or CLEAR-CLIP).

2023

m6A-eCLIP Data Sheet

m6A-eCLIP optimizes the enhanced crosslinking and immunoprecipitation (eCLIP) approach to profile m6A RNA modification sites transcriptome-wide with single nucleotide resolution. m6A-eCLIP requires 100-fold less starting material compared to other m6A profiling methods and yields more precise sites.

2023

eRibo Pro Data Sheet

The eRibo Pro service is an end-to-end solution that streamlines the ribosomal profiling process, from sample processing to sequencing and data analysis. The comprehensive service includes mapping of ribosome protected fragments (RPFs) and identification of differentially transcribed and translated genes with interactive reports that allow researchers to make data driven insights.

2023

eSHAPE Single RNA Data Sheet

eSHAPE Single RNA is a method to obtain mRNA structure probing data for in vitro transcribed mRNA formulations. In vitro transcribed mRNAs are used as input for RNA structure probing with the NAI reagent. eSHAPE Single RNA is available as a full service offering with results delivered as a data package containing RNA structure information as mutations and reactivities.

2023

5′ End-Seq Data Sheet

5′ End-Seq facilitates active transcript end detection, enrichment and mapping, and identifies known and novel transcription start sites at single nucleotide resolution in only 2 days.

2023

3′ End-Seq Data Sheet

3′ End-Seq is a technology for defining 3′ ends of transcripts by sequencing from the PAS. 3′ End-Seq can identify high confidence, known and novel PAS at single nucleotide resolution in 2 days