In this webinar, we will discuss two assays optimized by Eclipsebio to accelerate both academic discoveries and biopharma advancements: eRibo Pro (RiboSeq) to quantitate ribosome occupancy across a transcript, and eSHAPE (SHAPE MaP) chemical probing to accurately predict RNA secondary structure.
Webinar Information
About the Webinar
Title: Interrogating RNA Structure and Translation Dynamics with SHAPE and Ribosome Profiling
Date: Thursday, September 21
Time: 9:00AM – 10:00AM PST
Location: Virtual
Presenters:
Wayne Doyle, Ph.D
Stephanie Bruns, Ph.D
Registration Deadline:
September 20, 2023
Already Registered? Click Below to Join the Webinar on September 21 at 9AM PST
You will learn about the following services we provide:
ㅤeRibo Pro™ | RiboSeq
• Profile ribosome occupancy across an entire transcript.
• Identify genes that are differentially translated.
• Identify upstream (uORF), downstream (dORFs), and non-coding RNA ORFs.
• Identify sites of ribosome stalling and differential codon usage.
Eclipsebio is sole licensee of the Ribo-seq method covered by U.S. Patent Numbers 8,486,865, 9,284,547 and 9,677,068.
ㅤeSHAPE™ | SHAPE MaP
• Chemical probing of RNA to empirically determine secondary structure at single nucleotide resolution.
• Increased RNA structure prediction accuracy over folding algorithms alone.
Eclipsebio is sole licensee of NAI-based RNA structure methods covered by U.S. Patent Numbers 9,428,791 and 11,021,703.
ㅤRBP-eCLIP™ & miR-eCLIP™
• Map miRNAs and RBPs to endogenous and exogenous therapeutic transcripts in cells.
• Map locations of off-target siRNA binding.