Publications | Eclipsebio

Publications

Discover how our technologies have been applied

Our technologies and bioinformatics workflows have been used to obtain deep insights into different aspects of RNA biology, and our own scientific team frequently publishes on our newest capabilities. The following publications provide some examples of how our partners have utilized our capabilities to make groundbreaking discoveries. Contact us today to learn how we can help you achieve your therapeutic and research goals.

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miR-21: A therapeutic target for delaying severe liver disease and hepatocellular carcinoma in high-fat-diet-fed mice

Jagtap et al. bioRxiv

Autoregulated splicing of TRA2β programs T cell fate in response to antigen-receptor stimulation

Karginov et al. Science

AVJ16 inhibits the RNA binding protein IGF2BP1 in lung adenocarcinomas and prevents tumor growth in mice

Wallis et al. bioRxiv

Let-7 restrains an oncogenic epigenetic circuit in AT2 cells to prevent ectopic formation of fibrogenic transitional cell intermediates and pulmonary fibrosis

Seasock et al. bioRxiv

Systematic perturbation screens decode regulators of inflammatory macrophage states and identify a role for TNF mRNA m6A modification

Haag et al. bioRxiv

PRMT5-mediated arginine methylation of FXR1 is essential for RNA binding in cancer cells

Vijayakumar et al. Nature Communications