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Eclipsebio’s Series A Announcement
Eclipsebio Announces a $14 Million Series A Financing to Advance Its RNA Genomics Technology Platform RNA is increasingly the focus of medicine, new therapeutics, and
Eclipse Bioinnovations offers RNA genomics solutions with Next Generation Sequencing technologies to enable RNA to be seen in a whole new light. Simplify your RNA research with our suite of cutting-edge kits, services, bioinformatics, and custom solutions to unlock the potential of RNA.
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Evolving Solutions for Understanding RNA beyond RNA-Seq
Making New Discoveries in RNA Biology
Discover m6A modifications transcriptome-wide, map the miRNA-mRNA interactome at high-resolution, and deeply profile transcript ends with End-Seq.
Optimizing RNA Target Identification
Discover RNA binding protein (RBP) targets transcriptome-wide with eCLIP and generate high-resolution maps of RBP-RNA interactions.
Advancing Therapeutic Discovery
Robust and quantitative NGS genomics solutions to accelerate your pre-clinical research.
RBP-eCLIP
RBP-eCLIP enables reliable generation of high-throughput sequencing libraries from immunoprecipitated material to identify RBP binding sites on target RNAs with high resolution, transcriptome-wide.
miR-eCLIP
Discover the miRNA-mRNA interactome transcriptome-wide. miR-eCLIP unambiguously identifies miRNA target sites with precision and depth.
Expert RNA Bioinformatics
Our team of talented and experienced computational biologists use internally developed tools and pipelines to help you better understand your data and the underlying biology of your experiments.
FLI-Seq™
DNA Library Prep Solution for CRISPR Screens
From RNA Binding Proteins to RNA Therapeutics
Interview with Eclipse Bio Co-Founders, Gene Yeo and Peter Chu on the future of RNA led by eCLIP Technology
Powered by Eclipse Bio
My lab had a fantastic experience working with Eclipse BioInnovations. They made the experiment we sought to do approachable, and the staff was available to help and discuss the project every step of the way.
We approached Eclipse Bio because they were the only company that could perform the robust siRNA off-target binding analysis we needed. They were flexible with our needs and they developed all the experimental and computational tools for our project. Their experimental results provided important additional insights into our own internal findings and were clearly presented in a comprehensive report. Eclipse also provided plenty of helpful post-study support when we had questions or wanted to discuss the data. We look forward to continuing to work with Eclipse Bio in the future.
As compared to the other CLIP procedures, the eCLIP kit from Eclipse Bioinnovations includes several steps that improves identification of specific protein-nucleic acid interactions.This kit includes almost all necessary reagents as well as a very detailed protocol with essential explanations of the procedure, suggested stop points and potential trouble for each step of the procedure that makes you well prepared for a relatively long protocol, even if you do not have much experience with CLIP techniques.
I was very impressed by the quality of the libraries. Starting off with roughly 200 ng of mRNA, we obtained high-quality, complex libraries, on the basis of which we were able to identify thousands of m6A sites at single nucleotide precision.
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Eclipse Bio’s RBP-eCLIP™ kit has enabled the discovery of Ago2 particles forming from Gαq activation
Eclipse Bio’s RBP-eCLIP™ kit was cited in a recent publication, enabling the discovery of Ago2 particles forming from Gαq activation. Explore Advanced RNA Genomics Solutions.
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Eclipse Bio’s m6A-eCLIP™ service has enabled the discovery of Mettl3 as a p53-interacting protein.
Eclipse Bio’s m6A-eCLIP™ service was cited in a recent publication, enabling the discovery of Mettl3 as a p53-interacting protein. Explore Smarter RNA Genomics Solutions. Find