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eBlogs

Discover insights into RNA biology
and therapeutic development

In our monthly eBlog series, our team of RNA experts discusses the latest advances in RNA therapeutics, key discoveries in RNA biology, and methods for analyzing next-generation sequencing data. Read our blogs below to get insights directly from our wet lab and bioinformatics scientists.

Multiobjective sequence design for strong mRNA candidates 

For strong mRNA candidates, RNA design must move beyond solely codon optimization and utilize a multiobjective approach.

eCOMPASS: Onboarding an RNA therapeutic project with Eclipsebio 

eCOMPASS guides drug developers to the optimal candidate with its lap-in-the-loop platform.

Manufacturing-informed design in therapeutic development  

Successful lab-in-the-loop approaches optimize RNA therapeutic design to be easily manufactured and produced.

The power of pairing RNA design and analytics 

Discover how closed-loop RNA development pairs design and sequencing to accelerate better therapeutics.

Achieving regulatory requirements by measuring IVT RNA integrity 

As RNA therapeutics and regulatory requirements advance, validation methods for IVT RNA integrity are advancing as well.

RNA advancements and innovations: A 2025 review

In this latest eBlog, the Eclipsebio team looks back to some of the year's breakthroughs and ahead to future innovations.