Publications

Discover how our technologies have been applied

Our technologies and bioinformatics workflows have been used to obtain deep insights into different aspects of RNA biology, and our own scientific team frequently publishes on our newest capabilities. The following publications provide some examples of how our partners have utilized our capabilities to make groundbreaking discoveries. Contact us today to learn how we can help you achieve your therapeutic and research goals.

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Somatic DDX41 mutations confer neomorphic splicing activity in the pathogenesis of myelodysplastic neoplasms

Venkataraman et al. bioRxiv

The hnRNPA1 D262V amyotrophic lateral sclerosis (ALS) mutation is linked to mitochondrial dysfunction

Lee et al. Genes & Development

m6A mRNA methylation regulates pancreatic α-cell plasticity

De Jesus et al. Nature Metabolism

Cardiac fibroblast deletion of PTBP1 modulates the profibrotic response by alternative splicing

Ricketts et al. Nature Communications

Canonical and non-canonical miRNA degradation shapes state transitions and stemness in breast cancer

Rubolino et al. The EMBO Journal

The AGO2 adaptor LIMD1 expands the functional and evolutionary reach of microRNA targeting

Crozier et al. Science Advances