Publications

Discover how our technologies have been applied

Our technologies and bioinformatics workflows have been used to obtain deep insights into different aspects of RNA biology, and our own scientific team frequently publishes on our newest capabilities. The following publications provide some examples of how our partners have utilized our capabilities to make groundbreaking discoveries. Contact us today to learn how we can help you achieve your therapeutic and research goals.

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AAV delivery of artificial miRNA targeting MAPT for the reduction of tau pathology in Alzheimer’s disease

Hogestyn et al. Molecular Therapy

ECD functions as a novel RNA-binding protein to regulate mRNA splicing

Raza et al. bioRxiv

Cellular hierarchies of embryonal tumors with multilayered rosettes are shaped by oncogenic microRNAs and receptor–ligand interactions

Beck et al. Nature Cancer

Sequence based prediction of cell type specific microRNA binding and mRNA degradation for therapeutic discovery

Kanuparthi et al. bioRxiv

Nuclear Argonaute:miRNA complexes recognize target sequences within chromatin and silence gene expression

Hofman et al. Nucleic Acids Research

Validation of a microRNA profile in urine liquid biopsy with diagnostic and stratification value for bladder cancer classification, available through the open app BladdermiRaCan

Oto et al. Experimental Hematology & Oncology