Publications | Eclipsebio

Publications

Discover how our technologies have been applied

Our technologies and bioinformatics workflows have been used to obtain deep insights into different aspects of RNA biology, and our own scientific team frequently publishes on our newest capabilities. The following publications provide some examples of how our partners have utilized our capabilities to make groundbreaking discoveries. Contact us today to learn how we can help you achieve your therapeutic and research goals.

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Genome-wide CRISPR screens identify noncanonical translation factor eIF2A as an enhancer of SARS-CoV-2 programmed −1 ribosomal frameshifting

Wei et al. Cell Reports

An RNA foundation model enables discovery of disease mechanisms and candidate therapeutics

Celaj et al. bioRxiv

miRNA-1 regulation is necessary for mechanical overload-induced muscle hypertrophy in male mice

Fei et al. Physiological Reports

Aberrant splicing in Huntington’s disease accompanies disrupted TDP-43 activity and altered m6A RNA modification

Nguyen et al. Nature Neuroscience

5′ terminal nucleotide determines the immunogenicity of IVT RNAs

Wolczyk et al. Nucleic Acids Research

Next generation thiazolyl ketone inhibitors of cytosolic phospholipase A2 α for targeted cancer therapy

Ashcroft et al. Nature Communications