The 5’UTR of HCoV-OC43 Adopts a Topologically Constrained Structure to Intrinsically Repress Translation.

Cell culture is a frequently used model system for therapeutic development and basic research. Although it is a powerful tool, cell culture conditions can lead to significant changes in cell behavior. In our latest post, we review how cell density can affect gene expression and translation.

Eclipse Bioinnovations, Inc. (Eclipsebio), the leading RNA genomics company developing and commercializing novel, data-driven technologies and analyses that interrogate RNA, today announced the launch of its proprietary eMERGE™ platform.

Before release into the clinic mRNA therapeutics need comprehensive characterization. In this eBlog we review key quality attributes of mRNA therapeutics.

miRNAs are key regulators of expression and translation, however identifying where and how they bind can be a challenge. In this eBlog we reveal how miR-eCLIP can be used to directly profile miRNA activity.