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Our capabilities

Unique technologies for unmatched insights

Our portfolio of proprietary technologies and bioinformatics workflows provide actionable insights for therapeutic characterization and optimization. Discover how a partnership with us provides access to unparalleled techniques and analyses.

Empirical data for actionable insights

To solve the needs of our partners, we have developed a comprehensive suite of technologies that provide unparalleled data on key aspects of RNA biology and therapeutic activity. Discover the power of data-based insights over computational predictions.

Bioinformatics

Advanced analyses for actionable insights

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Overview

Use:

Integrative analysis of sequencing data from our portfolio of technologies

Example analyses:

Peak calling, motif identification, differential effects, RNA folding, differential stalling, codon usage

Learn More About Bioinformatics

End-Seq

Discover active UTRs

Learn More About End-Seq

Overview

Use:

Assess UTR usage

Typical species:

Human, mouse

Typical samples:

Total RNA

Learn More About End-Seq

eRibo Pro

Reveal transcription and translation

Learn More About eRibo Pro

Overview

Use:

Measure transcription (RNA-Seq) and translation (ribosome profiling)

Typical species:

Human, mouse

Typical samples:

Cells, tissues

Learn More About eRibo Pro

eSENSE dsRNA

Measure and reduce dsRNA contamination

Learn More About eSENSE dsRNA

Overview

Use:

Quantify dsRNA, optimize RNA sequences

Typical species:

Viral, human

Typical samples:

IVT RNA

Learn More About eSENSE dsRNA

eSENSE m6A

Locate regions of RNA methylation transcriptome-wide

Learn More About eSENSE m6A

Overview

Use:

Map methylated regions

Typical species:

Human, mouse

Typical samples:

Total RNA

Learn More About eSENSE m6A

eSHAPE

RNA secondary structure revealed

Learn More About eSHAPE

Overview

Use:

RNA secondary structure, nucleotide accessibility

Typical species:

Human, mouse, IVT sequences

Typical samples:

In vitro, LNP-encapsulated, and cellular RNA

Learn More About eSHAPE

m6A-eCLIP

Locate base-specific RNA methylation transcriptome-wide

Learn More About m6A-eCLIP

Overview

Use:

Map methylated bases

Typical species:

Human, mouse

Typical samples:

Total RNA

Learn More About m6A-eCLIP

miR-eCLIP+

Identify where and how miRNAs and siRNAs bind

Learn More About miR-eCLIP+

Overview

Use:

Map miRNA and siRNA binding

Typical species:

Human, mouse

Typical samples:

Cells, tissue

Learn More About miR-eCLIP+

Nanopore

Unlock long-read sequencing

Learn More About Nanopore

Overview

Use:

Direct RNA characterization

Typical species:

Viral, human

Typical samples:

IVT RNA

Learn More About Nanopore

RBP-eCLIP

Map where proteins bind across the transcriptome

Learn More About RBP-eCLIP

Overview

Use:

Map protein binding sites

Typical species:

Human, mouse, rat

Typical samples:

Cells, tissues

Learn More About RBP-eCLIP

Need additional support?

At Eclipsebio we value innovation and are continually developing new assays and workflows to improve therapeutic development. If you would like to obtain early access to our newest capabilities or need support that isn’t listed above, contact us today.

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