eSHAPE Single RNA is a method to obtain mRNA structure probing data for in vitro transcribed mRNA formulations. In vitro transcribed mRNAs are used as input for RNA structure probing with the NAI reagent. eSHAPE Single RNA is available as a full service offering with results delivered as a data package containing RNA structure information as mutations and reactivities.
miR-eCLIP enables the identification of direct miRNA-mRNA interactions transcriptome wide utilizing AGO2 immunoprecipitation, RNA-RNA ligation, and high-throughput sequencing (similar to methods such as CLASH or CLEAR-CLIP).
m6A-eCLIP optimizes the enhanced crosslinking and immunoprecipitation (eCLIP) approach to profile m6A RNA modification sites transcriptome-wide with single nucleotide resolution. m6A-eCLIP requires 100-fold less starting material compared to other m6A profiling methods and yields more precise sites.
The eRibo Pro service is an end-to-end solution that streamlines the ribosomal profiling process, from sample processing to sequencing and data analysis. The comprehensive service includes mapping of ribosome protected fragments (RPFs) and identification of differentially transcribed and translated genes with interactive reports that allow researchers to make data driven insights.
miR-eCLIP Research Summary: Using miR-eCLIP to Identify microRNA Targets Involved in Skeletal Muscle Disease
eSHAPE Research Summary: Using Chemical Probing to Determine the Structure of a Viral 5’ UTR and its Function in Translational Regulation
Explore your RNA Structure insights interactively, see the example report for eSHAPE db-K562
