Eclipsebio | RNA Genomics Technologies

Comprehensive RNA Genomics Technologies To Interrogate RNA Interactions

Eclipsebio’s Technologies

Our RNA Interrogation Solutions

Whether you are working on novel discoveries or developing next-generation RNA therapeutics, Eclipsebio’s RNA genomics platform has you covered from end-to-end

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GAIN WHOLE TRANSCRIPTOME DISCOVERY OF:

ㅤRBP-eCLIP: RBP Binding Sites

ㅤmiR-eCLIP: miRNA Targets

ㅤm6A-eCLIP: Map m6A Sites

ㅤeRibo Pro: Ribosome Profiling

ㅤeSHAPE: RNA Structure

ㅤEnd-Seq: 5’ & 3’ UTRs

What our customers say about us

“End-Seq assays are an invaluable part of our target assessment process at Ribometrix. The data are robust and often reveal novel 5’ and 3’ ends that aren’t reflected in public databases. Having this knowledge significantly influences strategic decisions around target selection in our RNA-targeting drug development process.”

Matt Smola, Ph.D., Associate Director.
Ribometrix

“My lab had a fantastic experience working with Eclipsebio. They made the experiment we sought to do approachable, and the staff was available to help and discuss the project every step of the way.”

Laura D. Attardi, Ph.D., Professor.
Stanford University School of Medicine

“Eclipsebio was the only company that could perform the robust siRNA off-target binding analysis we needed. Their experimental results provided important additional insights into our own internal findings. We look forward to continuing to work with Eclipsebio in the future.“

Alnylam Pharmaceuticals

“I was very impressed by the quality of the libraries. Starting off with roughly 200 ng of mRNA, we obtained high-quality, complex libraries, on the basis of which we were able to identify thousands of m6A sites at single nucleotide precision.“

Schragi Schwartz, Ph.D.
Weizmann Institute of Science

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Accelerating RNA Discovery for Researchers Around the World

PUBLICATIONS

2023 | miR-eCLIP

Discovery of novel microRNA regulators of ribosome biogenesis.

Bryant et al. bioRxiv

2023 | eSHAPE

The 5’UTR of HCoV-OC43 Adopts a Topologically Constrained Structure to Intrinsically Repress Translation.

Mackeown et al. Journal of Biological Chemistry

2022 | m6A-eCLIP

A functional screen of RNA binding proteins identifies genes that promote or limit the accumulation of CD138+ plasma cells.

Turner et al. eLife.

2021 | RBP-eCLIP

Activation of Gαq sequesters specific transcripts into Ago2 particles.

Jackson, et al. Research Square.

RNA Genomics Solutions to Accelerate RNA Research & Therapeutics Development