Virtual Webinar
Eclipsebio is honored to be invited to speak at the Boston Computational Society by sponsor biomodal, the webinar featured Dr. Wayne Doyle.The effective development of a therapeutic requires the ability to quickly and robustly validate that it is having expected actions on its target. In this webinar, Dr. Wayne Doyle, a senior Bioinformatics Scientist at Eclipsebio, reviewed two assays and analyses that can assist in the development of RNA therapeutics. eRibo Pro is a ribosome profiling assay for examining both transcription and translation in the same system. Dr. Doyle discussed Eclipsebio’s analyses for identifying changes in translation, pinpointing stalled ribosomes, and discovering translating open reading frames. miR-eCLIP +siRNA is an eCLIP-based method for directly identifying where miRNAs and siRNAs associate with genes across the transcriptome. Dr. Doyle reviewed how Eclipsebio determines miRNA binding, calls siRNA off targets, and identifies differential effects from siRNA modifications.
The recording of this webinar can be viewed here.
Summary
Purpose:
Learn about profiling siRNA binding and ribosome activity
Presenters:
Dr. Wayne Doyle (Senior Bioinformatics Scientist)
Date:
11 / 22 / 23