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# Eclipsebio

Accelerate RNA discovery to clinic

## Sitemaps

- [XML Sitemap](http://dev-eclipsebio.pantheonsite.io/sitemap.xml): Contains all public & indexable URLs for this website.

## Posts

- [Wacker Biotech and Eclipsebio Announce Strategic Collaboration to Advance RNA Medicine Development and Production](http://dev-eclipsebio.pantheonsite.io/news/press-release/wacker-biotech-and-eclipsebio-collaboration/) - The collaboration will combine Wacker Biotech's large-scale, GMP manufacturing with Eclipsebio's AI-driven RNA design and sequencing-based characterization.
- [Challenges in IVT scale-up ](http://dev-eclipsebio.pantheonsite.io/eblogs/challenges-in-ivt-scale-up/) - IVT scale-up poses several challenges, but comprehensive characterization can help produce a safe and effective mRNA therapeutic.
- [How eCOMPASS de-risks your RNA drug programs ](http://dev-eclipsebio.pantheonsite.io/eblogs/how-ecompass-derisks-your-rna-drug-programs/) - Learn how AI-powered design, rapid prototyping, and sequencing-based analytics in the eCOMPASS platform helps de-risk RNA therapeutic development.
- [RNA Delivery Prato 2026](http://dev-eclipsebio.pantheonsite.io/news/sponsor/2026-rna-delivery-prato/) - Eclipsebio is proud to sponsor the 2026 RNA Delivery Prato meeting to discuss recent discoveries and challenges in RNA delivery.
- [Eclipsebio Expands eCOMPASS™ Platform with eSENSE Break™ to Map RNA Fragmentation at Nucleotide Resolution](http://dev-eclipsebio.pantheonsite.io/news/press-release/eclipsebio-expands-ecompass-platform-with-esense-break-to-map-rna-fragmentation-at-nucleotide-resolution/) - Eclipsebio's eSENSE Break maps RNA fragmentation and circular RNA nicking sites at single-nucleotide resolution.
- [The power of pairing RNA design and analytics ](http://dev-eclipsebio.pantheonsite.io/eblogs/pairing-design-and-analytics/) - RNA drug development that follows the Design, Make, Test cycle creates effective therapeutics and provides data to advanced learning models.
- [Multi-objective sequence design for strong mRNA candidates ](http://dev-eclipsebio.pantheonsite.io/eblogs/multiobjective-sequence-design-for-strong-mrna-candidates/) - Intentional, multi-objective sequence design leads to strong mRNA candidates that are ready to manufacture at scale for the clinic.
- [2026 Data Catalyst Award Call for Applications](http://dev-eclipsebio.pantheonsite.io/news/grants/2026-data-catalyst-award-call-for-applications/) - The 2026 Data Catalyst Award offers matching funds for academic RNA profiling experiment. This year's focus: miRNA biology. Applications are now open.
- [Characterization is key: how to evaluate mRNA therapeutic safety and efficacy](http://dev-eclipsebio.pantheonsite.io/eblogs/mrna-characterization/) - Before release into the clinic, mRNA-based therapeutics need comprehensive characterization. In this eBlog we review approaches for the profiling mRNA drugs.
- [Eclipsebio Launches eCOMPASS™, an AI-Enabled Lab-in-the-Loop Platform for RNA Therapeutic Development](http://dev-eclipsebio.pantheonsite.io/news/press-release/eclipsebio-launches-ecompass/) - Eclipsebio's eCOMPASS platform combines AI-optimized design and sequencing-based analytics to de-risk RNA drug development.
- [eCOMPASS: Onboarding an RNA therapeutic project with Eclipsebio ](http://dev-eclipsebio.pantheonsite.io/eblogs/ecompass-onboarding-an-rna-therapeutic-project-with-eclipsebio/) - eCOMPASS offers an integrated lab-in-the-loop to design, make, and characterize optimized sequences for RNA therapeutic development.
- [Manufacturing-informed design in therapeutic development  ](http://dev-eclipsebio.pantheonsite.io/eblogs/manufacturing-informed-design/) - Considering the manufacturing process throughout RNA therapeutic development leads to high-quality and effective RNAs.
- [Eclipsebio Expands eMERGE™ Platform with eSENSE dsRNA™ for dsRNA Quantification and Localization](http://dev-eclipsebio.pantheonsite.io/news/press-release/eclipsebio-launches-esense-dsrna/) - Eclipsebio, the leader in developing precision solutions for RNA-based and RNA-targeting therapeutics, today announced the launch of its eSENSE dsRNA™ assay.
- [State of Eclipsebio - 2025](http://dev-eclipsebio.pantheonsite.io/eblogs/state-of-eclipsebio-2025/) - Read our CEO’s year in review highlighting major milestones, scientific advances, partnerships, and progress toward accelerating RNA therapeutic development.
- [How to find stalled ribosomes](http://dev-eclipsebio.pantheonsite.io/eblogs/ribosome-stall/) - During translation ribosomes can pause changing translation speed and causing frameshifts. In this blog we show how ribosome profiling can identify stall sites.
- [2026 mRNA Innovators Award Call for Applications](http://dev-eclipsebio.pantheonsite.io/news/grants/2026-mrna-innovators-award-call-for-applications/) - The mRNA Innovators Award offers matching funds to design and validate a novel mRNA sequence with Eclipsebio's trusted design and characterization methods.
- [High quality mRNA provides you with results that matter ](http://dev-eclipsebio.pantheonsite.io/eblogs/high-quality-mrna-provides-you-with-results-that-matter/) - Ensuring high quality mRNA during therapeutic development from design to verification reduces impurities and improves integrity.
- [Most mRNA design is flawed (and most vendors won't tell you) ](http://dev-eclipsebio.pantheonsite.io/eblogs/most-mrna-design-is-flawed/) - Effective mRNA design optimization considers the biological context of your mRNA, the cellular environment, and the characteristics of your target protein.
- [Notes from the lab: Spotting hydrolysis hotspots in mRNA ](http://dev-eclipsebio.pantheonsite.io/eblogs/spotting-hydrolysis-hotspots-in-mrna/) - Effective mRNA that considers expression and stability can identify and address specific design issues, such as hydrolysis.
- [Bringing sequence design out of the computer ](http://dev-eclipsebio.pantheonsite.io/eblogs/bringing-sequence-design-out/) - For truly powerful RNA therapeutic development, we must couple computational sequence design and experimental validation - "ex silico" development.
- [The million-dollar mistake: How bad mRNA design is burning your runway ](http://dev-eclipsebio.pantheonsite.io/eblogs/bad-mrna-design-is-burning-your-runway/) - Prioritizing the correct sequence design at the start of therapeutic development saves time and money to get an RNA therapeutic into the clinic.
- [The secret to your therapeutic success: Comprehensive mRNA design ](http://dev-eclipsebio.pantheonsite.io/eblogs/comprehensive-mrna-design/) - By comprehensively designing mRNA to optimize sequence, therapeutic effects, and manufacturability, developers can have a successful therapeutic in the clinic.
- [Design early or your mRNA program is doomed from the start ](http://dev-eclipsebio.pantheonsite.io/eblogs/design-your-mrna-early/) - Focusing on your mRNA design early in your therapeutic development can you accelerate timelines, reduce risk, and create high quality mRNA from the start.
- [Inside Eclipsebio’s design suite (or, why predictable mRNA design is so hard and how we do it anyway)](http://dev-eclipsebio.pantheonsite.io/eblogs/inside-eclipsebios-design-suite/) - Predictable mRNA design at Eclipsebio balances the optimization of performance and manufacturability based on your therapeutic goals.
- [Notes from the lab: I killed GFP](http://dev-eclipsebio.pantheonsite.io/eblogs/i-killed-gfp/) - A bad mRNA sequence can degrade or cause under expression in even the most stable proteins.
- [Eclipsebio Acquires Terrain Bio to Expand Its End-to-End AI Platform for the Design, Manufacturing, and Validation of RNA Therapeutics](http://dev-eclipsebio.pantheonsite.io/news/press-release/eclipsebio-acquires-terrain-bio/) - Eclipsebio extends its sequencing-based analytics platform into a fully integrated Design, Make, Test solution to accelerate the development of RNA medicines
- [Achieving regulatory requirements by measuring IVT RNA integrity ](http://dev-eclipsebio.pantheonsite.io/eblogs/measuring-ivt-rna-integrity/) - As regulatory requirements advance, measuring IVT RNA integrity is critical. Innovative sequencing-based methods can help developers meet these standards.
- [RNA structure analysis for improved drug development](http://dev-eclipsebio.pantheonsite.io/eblogs/rna-structure-drug-development/) - RNAs fold into complex structures, which can affect biology and drug efficacy. In this eBlog, we review the critical role of RNA structure on drug development.
- [Direct RNA sequencing for RNA therapeutic quality control](http://dev-eclipsebio.pantheonsite.io/eblogs/direct-rna-sequencing-for-rna-therapeutic-quality-control/) - Discover how long-read direct RNA sequencing advances RNA biology and provides critical quality control for RNA therapeutics.
- [Small proteins, big health impacts - the biology of micropeptides](http://dev-eclipsebio.pantheonsite.io/eblogs/micropeptide-biology/) - Discover how micropeptides are reshaping our understanding of the proteome, drivint disease insights, and inspiring new therapeutics.
- [RNA advancements and innovations: A 2025 review](http://dev-eclipsebio.pantheonsite.io/eblogs/2025-in-review/) - Review some of this year's breakthroughs in RNA therapeutics research and look ahead to next year's innovations with Eclipsebio.
- [What Makes RNA Data Truly AI-Ready](http://dev-eclipsebio.pantheonsite.io/eblogs/what-makes-rna-data-truly-ai-ready/) - Discover what makes RNA data truly AI-ready, from reproducibility and multidimensional coverage to strong connections with functional outcomes.
- [Why outdated RNA characterization assays fall short for regulatory readiness](http://dev-eclipsebio.pantheonsite.io/eblogs/why-outdated-characterization-assays-fall-short/) - Traditional RNA assays leave blind spots in quality assessment. Discover how sequencing-based methods strengthen regulatory readiness.
- [How to use IGV: part 2](http://dev-eclipsebio.pantheonsite.io/eblogs/how-to-use-igv-2/) - In this follow-up eBlog, we go into advanced use cases for IGV including finding motifs and working with sessions.
- [The future of RNA medicines at the 5th mRNA Therapeutics Summit](http://dev-eclipsebio.pantheonsite.io/eblogs/the-future-of-rna-medicines-mrna-therapeutics-summit/) - Explore breakthroughs and challenges from the 5th Annual mRNA Therapeutics Summit, and what they mean for the future of RNA medicines.
- [Thanksgiving 2023: thankful for our customers and team](http://dev-eclipsebio.pantheonsite.io/eblogs/thanksgiving-2023/) - As we come towards the end of the year, we at Eclipsebio are taking time this Thanksgiving holiday to reflect on what we are grateful for in this eBlog.
- [Five reasons why RNA therapeutics can fail](http://dev-eclipsebio.pantheonsite.io/eblogs/5-reasons-why-rna-therapeutics-can-fail/) - RNA therapeutics are the future of medicine but can often fail during development. Discover five reasons for therapeutic failure and how to reduce the risks.
- [RBP-eCLIP peak calling](http://dev-eclipsebio.pantheonsite.io/eblogs/rbp-eclip-peak-calling/) - The goal of RBP-eCLIP is to identify where an RNA-binding protein(RBP) is binding, in this eBlog we review how to identify peaks of protein enrichment on genes
- [Discovering miRNA regulation with miR-eCLIP+](http://dev-eclipsebio.pantheonsite.io/eblogs/discovering-mirna-regulation-with-mir-eclip/) - A miRNA is a small noncoding RNA that regulates mRNA activity. With miR-eCLIP+, researchers and drug developers can directly measure where and how miRNAs bind.
- [Detection of functional small open reading frames with ribosome profiling](http://dev-eclipsebio.pantheonsite.io/eblogs/detection-of-functional-small-open-reading-frames-with-ribosome-profiling/) - Open reading frames (ORFs) are regions of the transcriptome that can associate with ribosomes to change translation. Detection of ORFs outside of traditional...
- [Precision medicine in action: the role of personalized cancer vaccines](http://dev-eclipsebio.pantheonsite.io/eblogs/precision-oncology/) - Learn how RNA is enabling precision oncology with personalized cancer vaccines. These therapies utilize the patient's own immune system to eliminate cancer.
- [Charting a New Era: How RNA Is Unlocking N‑of‑1 Cures](http://dev-eclipsebio.pantheonsite.io/eblogs/how-k-abe-shows-rnas-potential/) - Learn how the k-abe therapy showcases RNA’s power to turn a diagnosis into a personalized therapy in under a year and what it means for the future of medicine.
- [Eclipsebio Launches eVERSE™, a First-of-Its-Kind Comprehensive Portfolio of RNA-Focused Datasets for AI Model Success](http://dev-eclipsebio.pantheonsite.io/news/press-release/eclipsebio-launches-everse/) - The eVERSE™ portfolio provides provides actionable, multidimensional training data from Eclipsebio’s full suite of next-generation sequencing technologies.
- [Eclipsebio Expands Intellectual Property Portfolio to Support New Product Suites Designed to Probe RNA Structure and Reveal Ribosome Occupancy and RNA Modifications](http://dev-eclipsebio.pantheonsite.io/news/press-release/eclipsebio-expands-intellectual-property-portfolio-to-support-new-product-suites-designed-to-probe-rna-structure-and-reveal-ribosome-occupancy-and-rna-modifications/) - Eclipsebio announced the completion of exclusive and co-exclusive licenses for IP related to RNA structure probing, ribosome occupancy, and RNA modifications.
- [Eclipsebio Launches eRibo Pro™, a Ribosome Profiling Service to Obtain RNA Translation Data](http://dev-eclipsebio.pantheonsite.io/news/press-release/eclipsebio-launches-eribo-pro-a-ribosome-profiling-service-to-obtain-rna-translation-data/) - Eclipsebio, a leading provider of innovative RNA analysis solutions, announces the launch of its proprietary eRibo Pro™ service, an all-inclusive offering...
- [Eclipsebio Announces a $14 Million Series A Financing to Advance Its RNA Genomics Technology Platform](http://dev-eclipsebio.pantheonsite.io/news/press-release/eclipsebio-announces-a-14-million-series-a-financing-to-advance-its-rna-genomics-technology-platform/) - Eclipseio, the leading RNA genomics company today announced the close of an oversubscribed $14 million Series A financing
- [The three pillars of AI in RNA biology: why data is the hardest to get right](http://dev-eclipsebio.pantheonsite.io/eblogs/the-three-pillars-of-ai/) - Learn more about the three pillars of AI: compute, algorithms, and data. Multidimensional RNA data remains a challenge, although new solutions are available.
- [AI-driven RNA drug development: a new era of discovery](http://dev-eclipsebio.pantheonsite.io/eblogs/ai-drug-development/) - Explore how AI accelerates RNA-based drug development, from target discovery to siRNA design and manufacturing, with insights into key challenges and solutions
- [Designing better RNA medicines with artificial intelligence](http://dev-eclipsebio.pantheonsite.io/eblogs/designing-better-rna-medicines-with-ai/) - Discover how AI is transforming RNA medicine development by enabling improved sequence design for better efficacy and accelerating the time to clinical success.
- [2025 Data Catalyst Award Announcement](http://dev-eclipsebio.pantheonsite.io/news/grants/data-catalyst-award-2025/) - To support RNA researchers, Eclipsebio is product to announce the 2025 Data Catalyst Award. The award offers matching funds to cover the cost of control datasets.
- [RNA and AI Symposium 2024](http://dev-eclipsebio.pantheonsite.io/news/sponsor/rna-and-ai-symposium-2024/) - Eclipsebio is proud to announce their sponsorship of the inaugural RNA and AI Symposium in San Diego. The meeting will feature talks AI's role in RNA medicines
- [Decoding Microproteins Across Evolution and Disease](http://dev-eclipsebio.pantheonsite.io/news/sponsor/decoding-microproteins-across-evolution-and-disease-2025/) - Eclipsebio is proud to announce their sponsorship of the inaugural Gordon Research Conference on Decoding Microproteins Across Evolution and Disease in Barcelona.
- [mRNA therapeutics - a new era in replacing traditional treatments](http://dev-eclipsebio.pantheonsite.io/eblogs/mrna-therapeutics-replacing-traditional/) - mRNA therapeutics are fundamentally transforming the way we approach modern medicine. In this eBlog we review how mRNA is providing rapid and scalable solutions.
- [A look back at 2024: exciting advancements in RNA ](http://dev-eclipsebio.pantheonsite.io/eblogs/2024-in-review/) - Explore 2024’s RNA breakthroughs with Eclipsebio: including discoveries into RNA biology, novel therapies, and cutting-edge sequencing innovations.
- [2024 Thanksgiving Message from the CEO](http://dev-eclipsebio.pantheonsite.io/eblogs/2024-thanksgiving-message-from-the-ceo/) - Eclipsebio CEO Peter Chu's annual letter of thanks to the Eclipsebio team and partners for another year of RNA-breakthroughs and advancements.
- [RBP-eCLIP motif calling](http://dev-eclipsebio.pantheonsite.io/eblogs/rbp-eclip-motif-calling/) - Many RNA-binding proteins recognize specific sequences called motifs. In this eBlog we review how to identify these binding motifs in RBP-eCLIP data.
- [Detecting differential changes between conditions](http://dev-eclipsebio.pantheonsite.io/eblogs/eribo-pro-peak-differential-expression/) - A differential expression analysis is a statistical procedure that identifies differentially up or downregulated genes between two or more conditions...
- [RBP-eCLIP peak annotation](http://dev-eclipsebio.pantheonsite.io/eblogs/rbp-eclip-peak-annotation/) - RNA-binding proteins (RBPs) can bind to specific gene regions such 3' UTRs or introns. In this eBlog we review how to annotate peaks with specific gene features
- [Stranded libraries](http://dev-eclipsebio.pantheonsite.io/eblogs/stranded-libraries/) - Different library preparations can lead to different types of strandedness. In this eBlog we review the different types of stranded libraries.
- [Eclipsebio Launches eSHAPE™ Product Family to Provide RNA Structure Probing at AGBT 2023](http://dev-eclipsebio.pantheonsite.io/news/press-release/eclipsebio-launches-eshape-product-family-to-provide-rna-structure-probing-at-agbt-2023/) - Eclipsebio’s eSHAPE™ product family is a combination of services and databases, that facilitates the study of RNA secondary structure
- [How to use IGV: part 1](http://dev-eclipsebio.pantheonsite.io/eblogs/how-to-use-igv-1/) - IGV is a powerful tool for visualizing next-generation sequencing data. In this eBlog we review how to use IGV to visualize BAM files and bigWig tracks.
- [The spooky secrets of identifying protein:RNA interactions (Halloween eBlog)](http://dev-eclipsebio.pantheonsite.io/eblogs/the-spooky-secrets-of-identifying-protein-rna-interactions/) - Our RBP-eCLIP services can help you obtain meaningful data about your RBP of interest, learn more about RBP-eCLIP in our Halloween-themed eBlog.
- [2023: a year-in-review](http://dev-eclipsebio.pantheonsite.io/eblogs/2023-year-in-review/) - 2023 has been a great year for RNA and we expect that in 2024 we will continue to see the importance of RNA biology for health and disease. In this eBlog...
- [RNA UK 2024](http://dev-eclipsebio.pantheonsite.io/news/sponsor/rna-uk-2024/) - Eclipsebio is proud to announce their sponsorship of RNA UK 2024, the premier event for bringing experts in RNA biology together to discuss the latest in RNA.
- [Successful mRNA therapeutic design: optimizing for stability and translation](http://dev-eclipsebio.pantheonsite.io/eblogs/successful-mrna-therapeutic-design/) - An mRNA therapeutic need to be stable and translationally efficient, in this eBlog we review how the design features that ensure success.
- [Eclipsebio Launches eMERGE™ Platform, a Cutting-Edge End-to-End Solution for the Characterization and Optimization of RNA-Based Therapeutic Products ](http://dev-eclipsebio.pantheonsite.io/news/press-release/eclipsebio-launches-emerge/) - Eclipsebio's eMERGE™ platform is an end-to-end solution for the characterization and optimization of RNA-based vaccines and therapeutics.
- [Changes in translation: the effect of cell culture and confluency](http://dev-eclipsebio.pantheonsite.io/eblogs/translation-and-confluency/) - Discover how protein translation is affected by cell culture conditions, including cell confluency, in this eBlog.
- [Mechanisms of RNA Decay 2024](http://dev-eclipsebio.pantheonsite.io/news/sponsor/mechanisms-of-rna-decay-2024/) - Eclipsebio is proud to announce their sponsorship of the 2024 Mechanisms of RNA Decay conference in Lisbon, Portugal.
- [dsRNA by-products: a threat to effective RNA-based medicines](http://dev-eclipsebio.pantheonsite.io/eblogs/dsrna-overview/) - dsRNA by-products can lead to reduced therapeutic stability and translation. In this eBlog, we review how dsRNA is generated and how to reduce it.
- [Reducing off-target effects in siRNA: expert tips for better efficacy](http://dev-eclipsebio.pantheonsite.io/eblogs/sirna-off-target-strategies/) - In this eBlog we review the mechanisms of siRNA off-target interactions and outline strategies to minimize them and enhance therapeutic efficacy.

## Pages

- [Home page](http://dev-eclipsebio.pantheonsite.io/) - Eclipsebio combines AI-powered RNA design, prototyping, and sequencing analytics to de-risk RNA therapeutic programs. Trusted by 300+ partners.
- [RNA Insights](http://dev-eclipsebio.pantheonsite.io/rna-insights/) - Browse every episode of RNA Insights by Eclipsebio. Expert interviews on RNA therapeutics, RNA research, and the latest RNA industry news.
- [Pre-Validated Antibodies](http://dev-eclipsebio.pantheonsite.io/pre-validated-antibodies/) - Eclipsebio provides pre-validated antibodies for RBP-eCLIP, reducing variability and enabling faster, more reliable RNA-protein interaction mapping.
- [eCOMPASS](http://dev-eclipsebio.pantheonsite.io/ecompass/) - eCOMPASS integrates AI-driven RNA design, rapid prototyping, and sequencing-based characterization in one iterative loop. De-risk your program from sequence to lead.
- [About us](http://dev-eclipsebio.pantheonsite.io/about/) - Eclipsebio combines AI-powered RNA design and sequencing-based analytics into one integrated drug development platform. Trusted by 100+ partners since 2017.
- [Access May 2025 Immagina webinar](http://dev-eclipsebio.pantheonsite.io/access-2025-regulation-webinar/) - In this webinar with Immagina Biotechnology, we review sequencing-based approaches for studying tRNA loading into ribosomes and binding by regulatory proteins
- [Access RNA structure and translation webinar 2024](http://dev-eclipsebio.pantheonsite.io/access-2023-global-webinar/) - Learn more about the importance of RNA structure and ribosome dynamics for biological research and drug development with Eclipsebio's team of RNA experts.
- [Access advanced analytics for mRNA-LNP medicines webinar](http://dev-eclipsebio.pantheonsite.io/access-mrna-lnp-medicines-webinar/) - Learn more about using imaging and sequencing to gain insights into LNP characterization for mRNA-LNP medicines.
- [Access 2025 CRISPR webinar](http://dev-eclipsebio.pantheonsite.io/access-2025-crispr-webinar/) - Learn about sequencing-first approaches for designing and characterizing CRISPR therapies for successful gene editing.
- [Access 2025 cancer discovery webinar](http://dev-eclipsebio.pantheonsite.io/access-2025-cancer-discovery-webinar/) - Learn more about sequencing-based solutions for cancer drug discovery and validation, including the importance of measuring UTR usage and translation.
- [Contact us](http://dev-eclipsebio.pantheonsite.io/contact/) - For general inquiries, to contact sales, or for technical support, please fill out a form.
- [Subscribe to our newsletter](http://dev-eclipsebio.pantheonsite.io/subscribe/) - Subscribe to Eclipsebio's mailing list to receive the latest updates in RNA therapeutics, RNA biology, and Eclipsebio.
- [Antibody validation request](http://dev-eclipsebio.pantheonsite.io/antibody-validation-request/) - With Eclipsebio's antibody validation service, an antibody is tested to confirm that it can robustly and reproducibly IP a protein of interest for RBP-eCLIP.
- [Access miRNA webinar August 2025](http://dev-eclipsebio.pantheonsite.io/access-mirna-webinar-august-2025/) - Watch our webinar with Dr. David Corey from UT Southwestern on miRNA interactions and their impact on gene regulation and RNA therapeutic research.
- [Leadership](http://dev-eclipsebio.pantheonsite.io/leadership/) - Eclipsebio’s leadership and advisory team combine expertise in RNA biology, biopharma, and executive management to advance RNA medicine innovation.
- [Careers](http://dev-eclipsebio.pantheonsite.io/careers/) - Eclipsebio is looking for dynamic and talented people to join our fast-growing team.

## Capabilities

- [m6A-eCLIP](http://dev-eclipsebio.pantheonsite.io/capabilities/m6a-eclip/) - Eclipsebio’s m6A‑eCLIP assay maps RNA methylation at single-nucleotide resolution, providing detailed insights for research and drug discovery.
- [eSENSE m6A](http://dev-eclipsebio.pantheonsite.io/capabilities/esense-m6a/) - Eclipsebio's eSENSE m6A assay is an enhanced version of MeRIP-Seq for the identification of methylated regions of RNA across the transcriptome.
- [IVT RNA Manufacturing](http://dev-eclipsebio.pantheonsite.io/capabilities/ivt-rna-manufacturing/) - Enable faster RNA drug development with lab-in-the-loop RNA prototyping and a seamless path to scale through trusted manufacturing partners.
- [IVT RNA Analytics](http://dev-eclipsebio.pantheonsite.io/capabilities/ivt-rna-analytics/) - Gain actionable insights into IVT RNA quality and performance with eMERGE, combining sequencing-based analytics across key RNA attributes.
- [RNA drug design](http://dev-eclipsebio.pantheonsite.io/capabilities/rna-drug-design/) - Accelerate RNA drug design with AI-driven, lab-in-the-loop optimization that balances manufacturability, stability, and expression.
- [eSENSE Break](http://dev-eclipsebio.pantheonsite.io/capabilities/esense-break/) - Map RNA fragmentation at single-nucleotide resolution with eSENSE Break. Pinpoint where breaks occur, diagnose the cause, and act on positional data.
- [eSENSE dsRNA](http://dev-eclipsebio.pantheonsite.io/capabilities/esense-dsrna/) - Eclipsebio identifies and quantifies dsRNA impurities with sequencing-based precision, empowering drug developers to create more effective RNA therapies
- [RBP-eCLIP](http://dev-eclipsebio.pantheonsite.io/capabilities/rbp-eclip/) - RBP-eCLIP maps RNA-binding protein interactions transcriptome-wide, revealing regulatory networks and supporting both research and therapeutic design.
- [Bioinformatics](http://dev-eclipsebio.pantheonsite.io/capabilities/bioinformatics/) - Eclipsebio offers advanced RNA bioinformatics and analytics, including QC, secondary analyses, and interactive reports for actionable insights.
- [End-Seq](http://dev-eclipsebio.pantheonsite.io/capabilities/end-seq/) - End‑Seq maps 5′ and 3′ UTRs at single‑nucleotide resolution, helping researchers and drug developers profile the UTR landscape in health and disease.
- [eRibo Pro](http://dev-eclipsebio.pantheonsite.io/capabilities/eribo-pro/) - Eclipsebio offers ribosome profiling services with eRibo Pro, providing sequencing-based insights into translation dynamics, stalling, and codon usage.
- [eSHAPE](http://dev-eclipsebio.pantheonsite.io/capabilities/eshape/) - Eclipsebio's eSHAPE assay maps RNA secondary structure in vitro, in LNPs, and in cells for research and drug development.
- [miR-eCLIP](http://dev-eclipsebio.pantheonsite.io/capabilities/mir-eclip/) - miR‑eCLIP+ identifies where miRNAs and siRNAs bind across the transcriptome, enabling precise target mapping for research and therapeutic validation.
- [Nanopore sequencing](http://dev-eclipsebio.pantheonsite.io/capabilities/nanopore-sequencing/) - Eclipsebio provides RNA assessments with Oxford Nanopore long-read sequencing to detect impurities and modifications that impact therapeutic quality.

## Solutions

- [RNA Therapeutic Solutions](http://dev-eclipsebio.pantheonsite.io/solutions/rna-therapeutic-solutions/) - From targeted support to a full design-make-characterize platform, Eclipsebio supports RNA therapeutic programs at every stage. Explore how we fit your program.
- [Small Oligonucleotide Solutions](http://dev-eclipsebio.pantheonsite.io/solutions/small-oligonucleotide-solutions/) - Eclipsebio helps drug developers design and validate small oligonucleotides with off-target screening and functional potency assays for siRNAs and ASOs.
- [Small Molecule Solutions](http://dev-eclipsebio.pantheonsite.io/solutions/small-molecules-solutions/) - Discover and validate small molecule drug targets with sequencing-based insights into mechanism of action and off-target effects.
- [Basic Research Solutions](http://dev-eclipsebio.pantheonsite.io/solutions/basic-research-solutions/) - Eclipsebio offers reproducible RNA biology research solutions, from structure mapping to ribosome profiling, enabling deeper insights into RNA function.
- [eVERSE](http://dev-eclipsebio.pantheonsite.io/solutions/everse/) - eVERSE delivers AI ready and multidimensional RNA datasets covering structure, translation, and regulation for ML model training in RNA drug development.

## Events

- [RNA Technology and Therapeutics Symposium](http://dev-eclipsebio.pantheonsite.io/event/rna-technology-and-therapeutics-symposium/) - Join Eclipsebio to learn how lab-in-the-loop platforms integrate AI-optimized design with sequencing-based analytics to produce clinic-ready mRNA candidates.
- [AMM ASCENT 2026](http://dev-eclipsebio.pantheonsite.io/event/amm-ascent-2026/) - Join Eclipsebio to learn how our AI-optimized mRNA design, in-house prototyping, and sequencing-based analytics produce mRNA candidates ready for the clinic.
- [Advanced Analytics for mRNA-LNP Medicines](http://dev-eclipsebio.pantheonsite.io/event/advanced-analytics-for-mrna-lnp-medicines/) - In this webinar, Eclipsebio and ScopeSys discussed how visualization and sequencing methods reveal mRNA-LNP quality and heterogeneity.
- [RNA Society Annual Meeting](http://dev-eclipsebio.pantheonsite.io/event/rna-society-annual-meeting/) - At this conference, Eclipsebio will host a booth on how sequencing-based assays can provide insights into RNA research and therapeutic development.
- [TIDES USA 2026](http://dev-eclipsebio.pantheonsite.io/event/tides-usa-2026/) - In this invited talk, Eclipsebio will discuss how sequencing-based approaches provide deeper insights into IVT RNA drug products.
- [International mRNA Health Conference](http://dev-eclipsebio.pantheonsite.io/event/international-mrna-health-conference/) - Eclipsebio will give a talk on how their eCOMPASS platform supports the design and characterization of RNA-based therapies.
- [End-to-End Analytical Solutions for mRNA Therapeutics](http://dev-eclipsebio.pantheonsite.io/event/end-to-end-analytical-solutions-for-mrna-therapeutics/) - At this AMM-USP co-hosted workshop, Eclipsebio will discuss how sequencing offers analytical solutions for mRNA manufacturing and quality control.
- [DIA Oligonucleotide-Based Therapeutics Conference](http://dev-eclipsebio.pantheonsite.io/event/dia-oligonucleotide-based-therapeutics-conference/) - At this DIA-hosted conference, Eclipsebio will present on how sequencing-based assays can provide insights to support RNA therapeutic development.
- [De-Risking RNA Therapeutics with High-Resolution Sequencing](http://dev-eclipsebio.pantheonsite.io/event/ont-webinar-derisk-drug-dev/) - In this webinar, Eclipsebio and Oxford Nanopore Technologies will discuss how nanopore sequencing provides insights into RNA therapeutic quality.
- [Cutting Edge Approaches for Cancer Target Discovery and Validation](http://dev-eclipsebio.pantheonsite.io/event/cutting-edge-approaches-for-cancer-target-discovery-and-validation/) - In this webinar, Eclipsebio and Active Motif review cutting-edge approaches for identifying and validating cancer targets
- [Revealing RNA Biology: from tRNAs to RNA Regulation](http://dev-eclipsebio.pantheonsite.io/event/eclipsebio-immagina-may-2025/) - In this webinar, Eclipsebio and Immagina showcase RNA sequencing tools that uncover how tRNAs, proteins, and miRNAs regulate and shape RNA biology.
- [Detecting and Characterizing RNA Drug Candidates to Accelerate Therapeutic Development](http://dev-eclipsebio.pantheonsite.io/event/detecting-and-characterizing-rna-drug-candidates-to-accelerate-therapeutic-development/) - In this webinar, Eclipsebio and Rockland Immunochemicals explained how their complementary technologies can help develop effective oligonucleotide therapeutics.
- [mRNA Process Development & Manufacturing Summit](http://dev-eclipsebio.pantheonsite.io/event/mrna-process-development-manufacturing-summit-2026/) - Meet Eclipsebio at the mRNA Process Development & Manufacturing Summit to explore how sequencing supports better development of RNA therapeutics.
- [mRNA Analytical Development and Quality Control Summit](http://dev-eclipsebio.pantheonsite.io/event/mrna-analytical-development-and-qc-summit-2026/) - Meet Eclipsebio at the mRNA Analytical Development & Ql Summit to learn how sequencing-based analytics reveal insights into RNA quality and potency.
- [Festival of Genomics and Biodata](http://dev-eclipsebio.pantheonsite.io/event/festival-of-genomics-2026/) - Meet Eclipsebio at the Festival of Genomics & Biodata to explore how our RNA profiling insights accelerate therapeutic discovery and development.
- [Characterization of mRNA Drug Product](http://dev-eclipsebio.pantheonsite.io/event/characterization-of-mrna-drug-product/) - Watch this AMM-hosted webinar to see how sequencing reveals LNP mRNA drug product quality, from RNA structure in LNPs to time-course activity in cells.
- [Interrogating RNA Structure and Translation Dynamics with eSHAPE and Ribosome Profiling](http://dev-eclipsebio.pantheonsite.io/event/webinar-recording-interrogating-rna-structure-and-translation-dynamics-with-shape-and-ribosome-profiling/) - In this webinar, Eclipsebio's Bioinformatics team discusses unique technologies for examining RNA structure and translation.
- [Supporting Therapeutic Development with Ribosome Profiling and miRNA Probing](http://dev-eclipsebio.pantheonsite.io/event/webinar-supporting-therapeutic-development-with-ribosome-profiling-and-mirna-probing/) - In this webinar, Eclipsebio reviews technologies for measuring translation (eRibo Pro) and miRNA activity (miR-eCLIP) and their use for RNA therapeutics.
- [Characterizing CRISPR-Cas9 Experiments](http://dev-eclipsebio.pantheonsite.io/event/webinar-characterizing-crispr-cas9-experiments/) - In this webinar, Eclipsebio and Active Motif review different approaches for characterizing CRISPR-based gene editing.
- [Identifying and Prioritizing miRNA:RNA Interactions](http://dev-eclipsebio.pantheonsite.io/event/mirna-webinar-2025/) - In this webinar, Dr. David Corey and Eclipsebio discussed how chimeric eCLIP can be used to identify and prioritize miRNA:RNA interactions.
- [The Future of mRNA Medicine: How Advanced Data Empowers Cures](http://dev-eclipsebio.pantheonsite.io/event/webinar-future-mrna-medicine-2025/) - Join Eclipsebio, CSL Behring, and BioSpace to explore the future of mRNA medicine and how advanced data is shaping safer, more effective therapies.
- [mRNA-Based Therapeutics Summit](http://dev-eclipsebio.pantheonsite.io/event/mrna-based-therapeutics-summit-2026/) - Join Eclipsebio at the mRNA-Based Therapeutics Summit to explore how our RNA profiling capabilities support breakthroughs in RNA drug discovery and development.
- [Personalized Cancer Vaccine Summit](http://dev-eclipsebio.pantheonsite.io/event/personalized-cancer-vaccine-2025/) - During the Personalized Cancer Vaccine Summit, Eclipsebio will be presenting on our eMERGE platform for supporting successful vaccine development.
- [mRNA Process Development & Manufacturing Summit](http://dev-eclipsebio.pantheonsite.io/event/mrna-process-development-2025/) - Eclipsebio will be giving a talk at the mRNA Process Development Summit on our sequencing-first solutions for RNA therapeutic quality control.
- [RNA Leaders USA](http://dev-eclipsebio.pantheonsite.io/event/rna-leaders-usa-2025/) - During RNA Leaders, Eclipsebio will be presenting on our comprehensive solutions for the successful development of RNA-based and RNA-targeting medicines.
- [mRNA-Based Therapeutics Summit](http://dev-eclipsebio.pantheonsite.io/event/mrna-based-therapeutics-summit-2025/) - Eclipsebio will be giving a talk on how our eMERGE partnership platform provides actionable insights for RNA-based medicine development.
- [Computational RNA Design & Delivery Summit](http://dev-eclipsebio.pantheonsite.io/event/computational-rna-design-2025/) - Eclipsebio will be presenting on our portfolio of ready-to-download and custom datasets for training AI models for the successful design of RNA-based medicines.
- [Oxford Nanopore Biopharma Day 2025](http://dev-eclipsebio.pantheonsite.io/event/oxford-nanopore-biopharma-day-2025/) - Eclipsebio will be presenting at the Oxford Nanopore Biopharma Day on how we use direct RNA sequencing to measure RNA therapeutic quality.
- [RNA Society Annual Meeting](http://dev-eclipsebio.pantheonsite.io/event/rna-society-2025/) - Eclipsebio will be attending the annual RNA Society meeting to discuss our support for basic research into RNA biology.
- [TIDES USA](http://dev-eclipsebio.pantheonsite.io/event/tides-usa-2025/) - Eclipsebio will be presenting at TIDES USA on our solutions for RNA-based medicine characterization and training successful AI models for drug discovery.
- [OPT Congress](http://dev-eclipsebio.pantheonsite.io/event/opt-congress-2025/) - At the 10th Annual OPT Congress, Eclipsebio will be sharing information on our capabilities for characterizing, optimizing, and validating RNA therapeutics
- [NATi RNA Symposium](http://dev-eclipsebio.pantheonsite.io/event/nati-rna-symposium-2025/) - Eclipsebio will be attending the NATi RNA Symposium in Singapore to discuss our solutions for RNA research and drug development success.
- [RNA Symposium](http://dev-eclipsebio.pantheonsite.io/event/rna-symposium-2025/) - Eclipsebio will be attending the RNA Symposium at the University of Michigan to discuss our solutions for RNA-based and RNA-targeting medicine success.
- [mRNA Analytical Development & Quality Control Summit](http://dev-eclipsebio.pantheonsite.io/event/mrna-analytical-development-2025/) - At the mRNA Analytical Development & Quality Control Summit, Eclipsebio will present on our eMERGE platform for comprehensive quality control of RNA therapies
- [mRNA-Based Therapeutics Summit Europe](http://dev-eclipsebio.pantheonsite.io/event/mrna-based-therapeutics-summit-europe-2025/) - Eclipsebio will be presenting at the mRNA-Based Therapeutics Summit on our sequencing-first characterization platform for RNA-based medicine success.
- [RNA-Targeted Drug Discovery Summit](http://dev-eclipsebio.pantheonsite.io/event/rna-targeted-drug-discovery-summit-december-12-2024/) - Eclipsebio will be presenting a talk on our solutions for multiomic characterization of RNA targets at the RNA-Targeted Drug Discovery Summit.
- [mRNA Health Conference](http://dev-eclipsebio.pantheonsite.io/event/mrna-health-conference-2024/) - Eclipsebio will have a booth at the 12th International mRNA Health Conference where we will be providing information on our solutions for mRNA therapeutics
- [mRNA Process Development & Manufacturing Summit](http://dev-eclipsebio.pantheonsite.io/event/mrna-process-development-2024/) - Eclipsebio will be presenting at the 3rd annual mRNA Process Development and Manufacturing summit on their eMERGE platform for RNA characterization.
- [RNA Leaders USA](http://dev-eclipsebio.pantheonsite.io/event/rna-leaders-usa-september-4-5-2024/) - RNA Leaders brings RNA experts together to solve the biggest challenges in RNA therapeutics. Eclipsebio will be presenting on solutions for therapeutic success.
- [mRNA-Based Therapeutics Summit](http://dev-eclipsebio.pantheonsite.io/event/mrna-based-therapeutics-summit-july-29-31-2024/) - Eclipsebio will be presenting their comprehensive, end-to-end solutions for mRNA therapeutic characterization at the 4th Annual mRNA-Based Therapeutics Summit
- [BIO International Convention](http://dev-eclipsebio.pantheonsite.io/event/bio-international-convention-june-3/) - During BIO, Eclipsebio will be meeting with partners to discuss their multidimensional mRNA therapeutic characterization platform.
- [European mRNA Conference](http://dev-eclipsebio.pantheonsite.io/event/european-mrna-conference-june-26-27-2024/) - At the European mRNA Conference 2024, Eclipsebio will be giving a talk on our end-to-end solutions for mRNA therapeutic characterization.
- [Drug Discovery Nexus](http://dev-eclipsebio.pantheonsite.io/event/drug-discovery-nexus-may-8-9-2024/) - Eclipsebio will have a booth at the 20th BioPharma Drug Discovery Nexus Conference. Visit us to learn about our comprehensive solutions for RNA therapeutics
- [mRNA Analytical Development Summit](http://dev-eclipsebio.pantheonsite.io/event/mrna-analytical-development-summit-february-14-15-2024/) - At the mRNA Analytical Development Summit, Eclipsebio will be presenting a talk on our mRNA therapeutic solutions including a new dsRNA detection method.
- [RNA Leaders Europe](http://dev-eclipsebio.pantheonsite.io/event/rna-leaders-europe-2024/) - RNA Leaders brings RNA experts together to solve the biggest challenges in RNA therapeutics. Eclipsebio will be presenting on solutions for therapeutic success.
- [OPT Congress](http://dev-eclipsebio.pantheonsite.io/event/opt-congress-march-13-14-2024/) - At the 9th Annual OPT Congress, Eclipsebio will be sharing information on our capabilities for characterizing, optimizing, and validating RNA therapeutics
- [RNAi-Based Therapeutics Summit](http://dev-eclipsebio.pantheonsite.io/event/rnai-based-therapeutics-summit-february-14-15-2024/) - At the 5th Annual RNAi-Based Therapeutics Summit, Eclipsebio will be presenting a talk on our RNAi solutions including the identification of siRNA off-targets
- [RNA Society](http://dev-eclipsebio.pantheonsite.io/event/rna-society-may-28-june-2-2024/) - Eclipsebio will have a booth at the 29th Annual Meeting of the RNA Society. Visit us to learn about our unique portfolio of technologies to examine RNA biology.