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eBlogs

02
26
24

Successful mRNA therapeutic design: optimizing for stability and translation | eBlog

mRNA therapeutics have unlocked the potential for rapid responses to infectious disease, personalized treatments for cancer, and protein replacement for different diseases. To ensure efficacy, specific features need to be included in the therapeutic to promote stability, efficient translation, and to... [READ MORE]

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eBlogs

01
30
24

How to find stalled ribosomes | eBlog

Monitoring translation dynamics at the gene level can be effectively achieved by employing ribosome profiling techniques, such as Eclipsebio’s eRibo Pro technology...[READ MORE]

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eBlogs

12
21
23

2023: A Year-in-Review | eBlog

2023 has been an exciting year for RNA and Eclipsebio! The RNA genomics space experienced a number of successes—from fascinating publications to the Nobel Prize in Physiology or Medicine, the importance of RNA to biology and health continues to be... [READ MORE]

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eBlogs

12
07
23

How to Use IGV: Part II | Bioinformatics eBlog

Next-generation sequencing (NGS) libraries produced by Eclipsebio’s assays typically consist of reads derived from targeted RNA regions. A visualization tool allows you to see which genes are present in your samples of interest and, depending on the assay, which specific transcript regions are enriched...[READ MORE]

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eBlogs

11
22
23

Thanksgiving 2023: Thankful for our customers and team | eBlog

As we come towards the end of the year, we at Eclipsebio are taking time this Thanksgiving holiday to reflect on what we are grateful for. As we have asked our fellow team members what they are thankful for, two topics have come up again and again: our customers performing groundbreaking RNA research... [READ MORE]

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eBlogs

11
15
23

Detection of Functional Small Open Reading Frames with Ribosome Profiling  | eBlog

Open reading frames (ORFs) are regions of the transcriptome that have an in-frame start and in-frame stop codon. This means that if a ribosome was to start translating at the start codon and translocate every three bases from codon to codon... [READ MORE]

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